New Study uses a CRISPR-based screening approach to identify a new therapeutic target for acute myeloid leukemia. #UpennCAMB, ShiLab, PennCDB, BergerLab, PennCancer, PennEpiInst.
https://www.pennmedicine.org/news/news-releases/2021/august/crispr-screening-tool-identifies-new-drug-target-for-leukemia
Our speckles paper led by Kate Alexander is now in print! We think it’s specktacular!
Mysterious ‘nuclear speckle’ cell structures may help block cancers https://penntoday.upenn.edu/news/mysterious-nuclear-speckle-structures-inside-cells-enhance-gene-activity-may-help-block
Excited to share our research highlighting a new role for the transcription factor p53 in re-locating its target genes within the nucleus in relation to nuclear speckles, phase-separated nuclear bodies, that boost gene expression of select target genes.
https://www.cell.com/molecular-cell/fulltext/S1097-2765(21)00174-X
Mysterious “nuclear speckle” structures inside cells enhance gene activity and may help block cancers:
https://www.pennmedicine.org/news/news-releases/2021/april/mysterious-nuclear-speckle-structures-inside-cells-enhance-gene-activity-may-help-block-cancers
